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Iberoamerican Journal of Medicine

Iberoamerican Journal of Medicine (Iberoam J Med) (ISSN: 2695-5075) is a peer-reviewed open-access international journal without any submission and publication fees. Iberoamerican Journal of Medicine publishes interesting original research conducted in all fields of medicine, interesting case reports and clinical images, reviews, editorials, letters, comments and letters to the Editor including reports on publication and research ethics. Iberoamerican Journal of Medicine encourages and enables a...



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Worm infestation issue is a common health condition observed mostly in Asian countries. The prevalence of worms in children is higher due to the habit of playing in mud or outdoors which is not found in the case of an infant. Very rarely worm infestation is observed in infants. There is a need for an investigation to be carried out for live worms in the stool. Sometimes the change in the diet of the infant, irregular bowel movements, and worm-like things in stool makes an alarming situation. We...
Topics: Worm, Infant, Banana fibers, Stool
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NAD(P)H:quinone oxidoreductase 1 (NQO1) is considered as one of the most significant enzyme in cellular defense due to its ability to detoxify reactive quinones and quinone imines to their less toxic hydroquinones forms. NQO1 is a xenobiotic metabolizing cytosolic enzyme that catalyzes the reduction of two- or four-electron of numerous exogenous and endogenous quinones by utilizing flavin adenine dinucleotide (FAD) as a cofactor. NQO1 enzyme exists as a homodimer enzyme and is biochemically...
Topics: Gene expression, NQO1, Keap1, ARE
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Simulation-Based Learning is considered the best alternative teaching and assessment tool that able to make the change in education, training, improving the quality and assessing the performance of the medical students. It helps students for acquiring many skills such as professionalism, communication, self-evaluation, time management, and teamwork. In addition, the use of simulation in medical education is based on many noble goals and ethical rules; it provides the best standards for patient...
Topics: Simulation, Obstacles, Challenges, Medical Education
Introduction : Public health security is concerned with infection prevention and control worldwide. These measures are the concern of all and sundry to ensure prevention of any outbreaks of diseases that has epidemic potential. Africa may be uniquely positioned to have the most severe and under-detected outcomes related to COVID-19 infection. This article seeks to highlight such challenges of healthcare delivery systems in the context of the COVID-19 pandemic in sub-Saharan Africa. The...
Topics: COVID-19, Preparedness, SARS-CoV-2, Resource-Constrained Settings, HealthCare Systems, Sub-Saharian...
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Introduction : Pressure ulcers (PU) are a major health problem, causing increased health costs as well as workload of health workers. In this study, we aimed to analyze the developments in PUs and to add perspective to future studies by examining the research articles published on PUs, which is an increasing health problem worldwide. Material and methods : Bibliometric analysis method was used in this study. The data was obtained by searching the Elsevier Scopus database with using the keywords...
Topics: Pressure ulcers, Bibliometric method, Scopus database
During December 2019, a rapid increase in the number of SARS-CoV-2 (COVID-19) cases was reported worldwide. We investigated several factors for rapid increase in SARS-COV-2. Genomic sequence reveals that domestic and wild animals were likely ancestors and zoonotic source for SARS-CoVs, MERS-CoVs, and SARS-CoV-2; these viruses replicated in animals and humans during past several decades, exhibiting diverse mutations and self-limiting diseases except during outbreaks. SARS-CoV-2 has been...
Topics: SARS-CoV-2, RT-PCR, Antibody, Zoonotic, Animal transmission, Genomics, Asymptomatic fraction, Herd...
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Central precocious puberty (CPP) is a rare disease. The mean annual incidence in girls is 0.8-1.1/100,000 and in boys 0-0.1/100,000. Intracranial arachnoid cysts (ICACs) are usually congenital and represent 1% of intracranial masses in newborns. Intraventricular location is rare. The objective of this work is to carry out a literature updated review of the coexistence of CPP and intraventricular arachnoid cyst (IVAC). ICACs are usually asymptomatic but can present with CPP in 10-40% of...
Topics: Central precocious puberty, Intraventricular arachnoid cyst, Children, Rare diseases, GnRH test,...
Introduction : During COVID-19 outbreaks, disproportionate use of antibiotics, high Intensive Care Units burden and longer in-hospital stays may have aggravated the emergency posed by carbapenem-resistant isolates. Therefore, we set out to determine whether the incidence of carbapenem-resistant isolates rose in a tertiary care center in Santa Fe, Argentina during the period with active cases of COVID-19. Material and methods : In this retrospectively designed analytic epidemiologic study, two...
Topics: Carbapenem-resistant Enterobacteriaceae, Antibiotic resistance, COVID-19, SARS-CoV-2, Outbreak
The COVID-19 pandemic and the limited therapeutic arsenal available strain daily clinical practice. Guidelines have recently recommended routine anticoagulation of hospitalized COVID-19 patients. However, apart from the expert panels’ experience, the provenance of this recommendation is not clear, due to the scarce published evidence. We provide a narrative review with the objective of unraveling the rationale for this practice. First, we analyze the biochemical, histopathological and...
Topics: COVID-19, SARS-CoV-2, Thrombosis, Anticoagulation
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The Objective Structured Clinical Examination (OSCE) is considered a gold standard summative and formative assessment method wherein it is a comprehensive and standardized tool assessing the clinical competencies including psychomotor domain, attitudes, and behaviors that will be manifested in the real work of the medical graduates. Therefore, the implementation of OSCE depends on the design of a blueprint that consists of two axes; the first axis is the tested competencies according to the...
Topics: Objective structured clinical examination, Educational assessment, Medical education, Clinical...
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World Health Organization (WHO) is gathering the latest scientific findings and knowledge on coronavirus disease (SARS-CoV-2) and compiling it in a database. WHO update the database daily from searches of bibliographic databases, hand searches of the table of contents of relevant journals, and the addition of other relevant scientific articles that come to our attention. The entries in the database may not be exhaustive and new research will be added regularly. Nobel coronavirus investigators,...
Topics: SARS-CoV-2, Coronavirus, Antivirals
Introduction : Recent studies have shown that the intestinal microbiota can modulate certain systemic metabolic and immune responses, including liver graft function and the development of complications in patients after liver transplantation (LT). Akkermansia muciniphila (AKM) and Faecalibacterium prausnitzii (FAEP) are two of the most abundant gut commensal bacteria, with mucosa-protective and anti-inflammatory effects that are important for maintaining normal intestinal homeostasis and gut...
Topics: Akkermansia muciniphila, Faecalibacterium prausnitzii, Gut microbiota, Liver transplantation,...
Objective : This article aims to explore the role and responsibility of physicians in the era of social media; the authors take as an example of the current pandemic of Coronavirus disease 2019 (COVID-19). Also, we highlight how social media impact the way populations trust and follow the recommendations of the governments. Methods : We identified relevant articles to date using a manual library search, journal publications on the subject, and critically reviewed them. Results : We critically...
Topics: Coronavirus Disease, COVID-19, Health Professionals, Health Policy, Social Media, Twitter,...
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Introduction : Urinary Tract infection (UTI) is considered as the most common infections disease among women. UTI may lead to a serious complication in both kidneys. In this study, we tried to determine whether the alternation in platelet count during UTI is related to specific Gram-type of bacteria causing the infection. This assists the medical staff in selection of suitable antimicrobial drug. Material and Methods : Data of all urine cultures from Gynecology Department/ Albaraa...
Topics: Urinary tract infection, Women, Platelet count, Bacteria, Gram-type
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Recently, an upsurge in the incidence of several emerging infectious diseases is causing great challenges to the health professionals throughout the globe. Since early 2020, an outbreak of coronavirus disease 2019 (COVID-19), now a pandemic, is hitting the world severely. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative agent of COVID-19, gain entry through the respiratory systems (nasopharyngeal) route causing infection. This disease is reported from all continents...
Topics: Coronavirus, COVID-19, Emerging infectious disease, Public health, RT-PCR, SARS-CoV-2
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Introduction : The relationship between inflammation and cancer has long been the focus of researchers' interest. There are many inflammatory markers studied for this purpose in the literature. In this context, we focused on the effects of platelet counts and platelet mass index (PMI) as inflammatory markers in the diagnosis of low-volume localized testicular cancer. Materials and methods : Thirty-eight patients with localized testicular cancer with a mean age of 30.84 ± 5.79 years and 38...
Topics: PMI, Testicular tumours, Biomarkers
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The outbreak of novel Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic and a public health crisis. COVID-19 is the clinical manifestation of infection with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Although it is predominantly a respiratory illness, there is growing awareness of the cardiovascular manifestations of COVID-19 disease. Patients with pre-existing cardiovascular co-morbidities appear to be at highest risk for mortality from this disease along...
Topics: COVID-19, SARS-CoV-2, Myocarditis, Heart failure, Arrhythmia
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Introduction : Face masks use among Cameroonians is a new behavior. Many citizens have adopted face masks as a step to prevent the spread of COVID-19. Individuals might use face masks because of their profession, risk perception, and social status. This study aims at evaluating the relation between occupation and face masks use in COVID-19 setting in Cameroon. Our study hypothesizes that face masks use is not associated with occupation in Cameroon. Methods : A survey was conducted from May 13...
Topics: Face masks, Coronavirus, Cameroon, COVID-19, Occupation, Behavior, Health professionals
Persistent urogenital sinus (PUGS) is an uncommon developmental cloacal anomaly, with Incidence of 0.6 in 10000 female births. Herein we depict the case of a 22-year of age lady who presented with Infertility for 16 months with dyspareunia and was found to have Persistent urogenital sinus associated with other urogenital anomalies as unilateral rudimentary horn with ipsilateral renal agenesis and contralateral dermoid cyst. The patient was successfully treated with the excision of the sinus,...
Topics: Urogenital sinus, Renal agenesis, Rudimentary horn
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Introduction : Amyand’s hernia is an extremely rare and atypical hernia that is difficult to diagnose clinically characterized by the herniation of the appendix into the inguinal sac. The aim of this report is to describe a case of Amyand’s hernia and highlights the importance of early CT scanning in reaching the exact and early diagnosis of Amyand’s hernia. Case report : We present a rare case of a 69-year-old female patient with a history of intermittent pain in the right inguinal...
Topics: Amyand’s hernia, Inguinal hernia, Appendix, Hernia sac, CT, Appendectomy
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Aluminum phosphide (ALP) is a highly toxic compound most commonly available as Celphos in Nepal. Suicidal ingestion is common in developing countries like Nepal as it is easily available and has a high mortality rate. Farmers to protect crops from rodents and pests use it. Here we present a case of a 24-year-old female with suicidal ingestion of one and a half-tablet of ALP presented with abdominal pain and vomiting. The patient developed metabolic acidosis, hyperkalemia, acute respiratory...
Topics: Aluminum phosphide, Suicidal ingestion, Metabolic acidosis, Acute respiratory distress, Magnesium...
This case report presents a lipofibromatous hamartoma of the median nerve in a 31-year-old man who presents local deformity and a sensory deficit in the nerve territory. The tumor was evaluated with magnetic resonance, computed tomography, and plain film radiography, studying the pathognomonic findings of this tumor. The patient did not want surgical treatment because of prior surgical sequelae. A prior surgical biopsy was reported as a peripheral nerve with normal axonal fascicles surrounded...
Topics: Lipofibromatous hamartoma, Median nerve, Carpal tunnel, Magnetic resonance, Macrodactyly
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Melkersson-Rosenthal syndrome (MRS) is a rare neuromucocutaneous granulomatous disorder classically defined by the triad: fissured tongue (lingua plicata), recurrent orofacial edema, and relapsing facial paralysis. Association with other dysimmune disorders was reported suggesting an immunological origin to this syndrome. The association with autoimmune thyroiditis remains exceptional and unusual. We report the original case of an MRS associated with Hashimoto autoimmune thyroiditis in a...
Topics: Melkerson-Rosenthal syndrome, Autoimmune thyroiditis, Hashimoto thyroiditis, Lingua plicata
Editorial
Topics: Emergency, Primary Care, Medicine
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Introduction : Although infective endocarditis (IE) is rare disease, this disease has importance due to its high morbidity and mortality rates. The exact incidence is not known as it is not a reportable disease. Unlike developed countries, the disease affects the young more than the elderly in developing countries. Most of the time, the diagnosis cannot be made at the first examination and the disease is often overlooked. In order to reduce the mortality and morbidity of this disease, it is...
Topics: Infective endocarditis, Bibliometric analysis, Scopus database
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Topics: Evidence-Based practice, Scientific studies, Medicine, Physycal therapy, Allied health
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Varicella Zoster (shingles) virus is a double stranded DNA in the Herpesviridae family that can present as both chicken pox and as shingles. The virus enters through the respiratory system, replicating in the nasopharynx, and causes a viremia upon primary infection. Varicella Zoster spreads to other organs and often lies dormant in the dorsal root ganglion. Reactivation of the virus is more common in older or immunocompromised patients and often presents as a painful vesicular rash in a...
Topics: Varicella zoster virus, Shingles, Urinary dysfunction
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Introduction : This experimental study gauged the value of argyrophilic nucleolar organizer region (AgNOR) staining as a possible technique for the estimation of cell kinetics in conventional histology sections, in benign and malignant breast lesions. Methods : With a silver staining technique and immunohistochemistry, we associated the numbers of AgNORs and Ki67 scores in 30 breast carcinomas and 10 benign breast lesions. Results : The mean values of Ag NORs silver stain dots count for normal,...
Topics: Breast cancer, AgNORs, Ki67, Benign, Malignant
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Introduction : Progranulin or acrogranin is an 88-kDa glycoprotein identified by a biological screen for protein targets associated with high tumorigenicity. This work was aimed to investigate the digital expression of GP88, and HER2/neu as a predictive biomarker in human invasive ductal carcinoma (IDC) versus benign tumors and normal breast tissues, as well as its correlation with different pathological parameters. Methods : The immunohistochemical avidin-biotin complex protocol of the...
Topics: HER2/neu, GP88, Clinical pathological parameter, Invasive ductal carcinoma, Immunohistochemical...
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Bladder cancer is one of the most significant genitourinary cancer characterized by a high rate of recurrences, morbidity, and mortality in a large number of patients. Over the years, numerous therapeutic approaches have been developed. For more than 40 years, the most comprehensive method for the treatment of non-invasive and invasive bladder cancer has been the use of Bacillus Calmette-Guerin (BCG), giving a successful effect in a high percentage of patients. However, due to the genetic...
Topics: Bacillus Calmette-Guérin, Bladder cancer, Checkpoint inhibitors, Immunotherapy urothelial carcinoma
Since the outbreak of the novel Coronavirus in December 2019 in Wuhan China, this novel Coronavirus disease(COVID-19) has spread worldwide taking not only epidemic proportions but with its rapid spread world health organization(WHO) was forced to declare it as a pandemic. The Severe Acute respiratory syndrome (SARS)-Coronavirus (CoV2) virus is responsible for clusters of severe respiratory illness that simulates acute respiratory syndrome that was what was initially. It is thought although that...
Topics: COVID-19, Pandemic, Diagnosis, Isolation, Hydroxychloroquine, Ivermectin, Convalescent plasma
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Change is a learning process modeling the attitudes and values of the involved staff to adapt and show the change in daily work life. Leading the change in medical schools or in the health care system is considered one of the assignments of successful leadership that can achieve an effective organizational change under complex conditions. This review aims to show an implementation view about how to manage the change in medical institutions and how to overcome obstacles, and how to face the...
Topics: Change, Management, Implementation, Medical institutions
Introduction : Tuberculosis infection caused by Mycobacterium tuberculosis is one of the most common infectious diseases, especially in countries such as Iran. The course of treatment and the number of drugs used vary depending on the severity of the disease and the parts of the body involved. The resistant tuberculosis to treatment has increased in recent years. Thus, this study was conducted to investigate the frequency distribution of response to treatment of patients with tuberculosis in...
Topics: Mycobacterium tuberculosis, Resistant tuberculosis, Treatment
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Introduction : With the increase of COVID-19 cases, an unusual manifestation for this type of virus began to appear anosmia and dysgeusia, which could indicate a neurologic alteration. In this context, it seems likely that subclinical manifestations of baroreflex involvement occur. The vegetative nervous system carries out the regulation of the baroreflex through the balance between sympathetic and parasympathetic activity. The objective of this study is to verify whether patients with COVID-19...
Topics: Dysautonomia, COVID-19, Heart rate variability
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Introduction : Cicatricial alopecias are a group of disorders characterized by hair follicle destruction with the consequence of permanent hair loss. The current study was conducted to evaluate the epidemiological and clinicopathological characteristics of cicatricial alopecia in Libyan community. Methods : Thirty-one patients with confirmed diagnosis of cicatricial alopecia by biopsy and tricoscopy during Jan 2018 to Dec 2019 were included in this study. Data were collected by filling a...
Topics: Cicatricial, Alopecia, Hair loss, Disorder, Lybia
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Introduction : Diabetes mellitus is a chronic metabolic disorder that induces elevated plasma glucose levels. Diabetic patients are more susceptible to infections, especially fungal infections. There is a direct relationship between increased blood glucose levels and the number of Candida hyphae in the oral mucosa. This study aimed to evaluate oral candidiasis and the different Candida species found in patients with and without diabetes mellitus. Methods : A search for studies on oral...
Topics: Blood glucose, Oral candidiasis, Diabetes mellitus, Risk factors
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Introduction : Oral and dental (OD) disorders in children with Rubinstein-Taybi syndrome (RTS) are frequent but not well-known by dentists and pediatricians due to the syndrome being extremely rare. Objective : To describe the OD findings observed in a 5-year-old girl with RTS and to update the literature. Clinical case : The patient presented the following OD manifestations: prominent lower lip, narrow mouth opening, narrow and arched palate, history of angular cheilitis, micrognathia, poor...
Topics: Rubinstein-Taybi syndrome, Odontostomatology disorders, Pediatric dentistry, Disabled persons,...
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Neurological disorders present a major group of diseases with the global prevalence of 6.3%. They are responsible for 12% global mortality. Mast cells are one of the most abundantly present cell of the immune system in the connective tissue and the central nervous system is not an exception. In this article is presented a review of studies on mast cells regarding their physiological role in cental nervous system. We also disscuss their role in several conditions like: multiple sclerosis,...
Topics: Central nervous system, Neuroimmunology, Mast cells, Histamine
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Topics: Telemedicine, COVID-19, Children, Pediatrics, Neurology
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Introduction : Dentin hypersensitivity (DH) is the most common concern faced by most dentists in their day-to-day clinical practice. It is characterized by short-term, acute pain of variable intensity, which occurs in response to thermal, tactile, osmotic or chemical stimuli that cannot be attributed to any other type of defect or dental decay. Casein phosphopeptide varnish is a newer material used to treat dentinal hypersensitivity as it reduces demineralization and promotes remineralization....
Topics: Casein phosphopeptide, Dentin hypersensitivity, Fluoride varnish, Visual analogue scale
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Mucormycosis is rare in both immunocompromised and immunocompetent patients. A Chronic Myelomonocytic Leukaemia (CMML) is among the most aggressive and poorly understood chronic myeloid malignancies, and Mucormycosis is an uncommonly encountered clinical syndrome in immunocompromised hematology patients. Patients treated with mechanical ventilation are at a substantially higher risk for infection. Also, the patients who are using home respirator devices at high risk for mucormycosis. Patients...
Topics: Pulmonary, Mucormycosis, Home-ventilator device, Chronic myelomonocytic leukaemia
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Topics: Graves’ ophtalmopathy, Graves’ disease, Hyperthyroidism
Introduction : Successful medical decisions are highly reliant on medical laboratory results; as such, laboratory results are essential to patient health management, and errors in those results may lead to serious complications and death. The aim of the present study was to assess the knowledge of medical laboratory practitioners in Saudi Arabia regarding factors that may influence medical laboratory testing results and the correct actions for troubleshooting. Methods : A total of 256...
Topics: Knowledge, Attitudes, Medical laboratory professionals, Non-pathological factors
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Introduction : The global burden of bacterial skin infection is substantial. We aimed to determine the common pathogens causes skin infections and their antimicrobial resistance pattern. Methods : A retrospective record review of data claimed from the microbiology department at Ber-Ustta Milad skin hospital between Jan 2009 to December 2018 was conducted. The consequence of interest was the antimicrobial sensitivity of bacterial isolates. Chi square was used for statistical analysis. Results :...
Topics: Bacteria, Skin, Infection, Libya
Introduction : There are very few studies on the effects of regular blood transfusions on the hemodynamic organization of patients with Beta-Thalassemia Major (BTM). Ambulatory Blood Pressure Monitoring is method that evaluates fluctuations in day-night periods and life cycle changes. In this study, we aimed to investigate the effects of blood transfusion on hemodynamic parameters by the Ambulatory Blood Pressure Monitoring method on the day of transfusion in patients with a diagnosis of...
Topics: Non-dipper, Thalassemia, Transfusion, Blood pressure
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Presentation of botulism in adults is extremely rare and symptoms can be easily confused for symptoms of acute stroke, Guillain-Barre, or myasthenia gravis. The purpose of this clinical case report is to ensure adult botulism will be included in the differential diagnoses for a patient with this presentation so swift and accurate care can be provided to ensure optimal patient outcome. A 41-year-old-female presented with complaints of sudden onset of difficulty speaking. The patient reports a...
Topics: Botulism, Botulism antitoxin, Differential diagnosis, Pharmaceutical preparations, Humans, Aftercare
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Introduction : Diabetes mellitus (DM) is a multifactorial metabolic disorder which is of public health concern. Therapeutic intervention using reliable, affordable and non-toxic natural sources is crucial. Aim of the study : This research was designed to evaluate the α-amylase and α-glucosidase inhibitory activities of ten essential oils from Calophyllum inophyllum Linn. The study is part of our local sourcing for natural promising leads to ameliorating diabetes mellitus globally. Materials...
Topics: Diabetes mellitus, Hyperglycemia, Medicinal plants, Calophyllum inophyllum, α-amylase inhibition,...
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Topics: Palatal tori, Oral torus, Oral bony exostosis, Adolescent woman
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ntroduction : The antimicrobial agents have saved human from several infectious disease. However, bacteria have capability to develop to become resistant to antibiotics and incorrect use of antibiotics is the main determinants of development of antimicrobial resistance which is a public health issue. Attention on medical students and community people should be emphasized by both education and promotion. Thus, this study was aimed to assess the present knowledge, attitude and behavior of Libyan...
Topics: Antibiotics, Bacteria, Community, Health education, Libya, Utilization, Students
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When a person with a head injury arrives at the hospital, doctors and nurses first check life signs: cardiac work, blood pressure and breathing. For those who do not breathe satisfactorily, a extractor fan may be required. Doctors immediately assess the patient's state of mind and memory. They also test the brain's basic functions by checking the size of the pupils and their response to light, assessing reactions to sensations such as heat and stab of the needle, and testing the ability to move...
Topics: Head, Brain, Damage, Diagnosis
Introduction : During COVID-19 pandemic, when social distancing becomes compulsory for all, a nation-wide school closure was implemented. The aim of this paper is to assess the impact of COVID-19 lockdown on children with ASD and their families in Tripoli, Libya. Materials and Methods : We conducted face-to-face interviews with parents of children with Autism Spectrum Disorder (ASD) during the period of the outbreak between June to December 2020. The Modified Check list of Autism in Toddlers...
Topics: Autism, COVID-19, Behaviour, Lockdown, Libya
Introduction : The hand harbors different species of bacteria that may play a role in the transmission of infectious diseases. Therefore, this study was conducted to determine the bacterial profile of hands and assess the efficacy of the three most common methods of hand cleansing on the reduction of that bacteria. Materials and methods : Hand swaps were collected from 150 adults. The identity of bacteria was done by standard microbiological procedures. Each participant applied one of three...
Topics: Hand hygiene, Handwashing, Sanitizer, Hand wipes
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Introduction : Aspirin has justifiably been called the first miracle drug. In this article, we highlight the history of Aspirin, a novel mechanism of action, and its use in cardiovascular and other diseases. Also included is a brief statement of emerging new applications. Objective : We highlight principal mechanisms by which Aspirin inhibits acute inflammation and alters platelet-biology; therefore, hypothesized that Aspirin might prove highly beneficial as a novel therapeutic drug for...
Topics: Aspirin, COVID-19, Systemic inflammatory response, Cytokine storm, Nonsteroidal antiinflammatory...
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After spillover from Wuhan (China) in December, 2019, SARS-CoV-2 related respiratory disease (COVID-19) has rapidly affected all countries. The pandemic has posed a serious threat to world health resources. At present, there is no recommended treatment or vaccine for SARS-CoV-2. However, various drug combinations are under trial. Reversion to general principles of prevention is the preferred strategy under such circumstances. We discuss the importance of wearing a face mask and present a...
Topics: COVID-19, SARS-CoV-2, Face mask, Pandemic, Protection
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Topics: Hemangioma, Infant, Child, Adolescent, Adrenergic Beta-antagonists
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Vesiculobullous lesions can be developed by less than 5% of patients with systemic lupus erythematosus (SLE). Among these lesions, bullous systemic lupus erythematosus (BSLE) is one of the rarest and most challenging cutaneous presentations of the disease. Its frequency in the largest series of 5149 patients with cutaneous lupus was 0.19%, and the majority of cases are reported as sporadic observation or small series not exceeding ten cases. We report the original observation of BSLE revealing...
Topics: Bullous systemic lupus erythematosus, Cutaneous lupus, Systemic lupus erythematosus, Skin
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Topics: Blood pressure, Atherothrombotic syndrome, Circadian rhythm
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Introduction : Coronavirus disease 2019 is the recent most devastating global outbreak that influenced humanity in the new millennium since decades from the last devastating pandemic. Despite being of low mortality rates - if compared with the previous epidemics in human history - the progressively spreading epidemic does not impact health and life but also has changed man's lifestyle, economy, politics and many other undisputed admitted daily routines. Methods : The present case provides...
Topics: CoVID-19, Pandemic, Polynomial regression, PHEIC
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Introduction : Recent advances in nanotechnology have introduced new therapeutic materials for periodontal therapy. Previous studies showed that nanoparticles of silver provide high antibacterial activity. Taking this in consideration, it can be used in nonsurgical periodontal therapy. The present study focuses on efficacy of subgingival local drug delivery of silver nanoparticles in comparison with tetracycline in chronic periodontitis. Methods : To understand the effect of silver...
Topics: Silver nanoparticles, Periodontitis, Chronic periodontitis
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : Stroke is defined as sudden onset of focal neurological deficit lasting more than 24 hours duration. There are several complications derived from these illness, including neurological disorders like gait dysfunction. Attending to this problem, some treatments have been developed, including ankle foot orthosis (AFO), knee gaiter and bobath intervention. The aim of this study is to compare the efficacy of functional task in patients affected by stroke. Material and Methods : Timed...
Topics: Functional Task, Bobath, Knee Gaiter, Gait dysfunction, Stroke
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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The practice of pharmacy in health care societies continues to undergo evolutionary and even radical changes. It has changed to a personal health service charged with assuring pharmaceutic and therapeutic appropriateness of all its functions in the care of patients. The purpose of this study is to review and analysis the historical stages of development of the good pharmaceutical practice (GPP) requirements and to recommend a guideline for the implementation of GPP standards in Libya as a way...
Topics: Libya, Pharmacies, Pharmacist, WHO
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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The objective of this review is to summarize specialty data regarding possible manifestations of diffuse idiopathic skeletal hyperostosis in general otorhinolaryngology practice in order to increase awareness of this entity. Research on the topic was based on consulting specialty books, electronic databases like PubMed, Scopus (Elsevier), Web of Science, Research Gate, Up-to-date and also, on clinical experience. Even though asymptomatic in most patients and many times found during cervical...
Topics: Dysphagia, Dyspnea, Diffuse idiopathic skeletal hyperostosis
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Topics: Coronavirus, COVID-19, Pandemic
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : Medicinal plants have been the most productive source of leads for the development of drugs from ancient times. Current research in drug discovery involves a multifaceted approach combining botanical, biological, and molecular techniques. Medicinal plant based drug discovery continues to provide novel and important leads against several diseases. Methods : Relevant articles relating to the concept were identified using a combination of manual library search as well as journal...
Topics: Medicinal plants, Coronavirus, Diseases, Health, Traditional medicine
Introduction : Phosphoinositides play a key role in the regulation of focal adhesions (FAs) turnover during cell adhesion and migration. However, their potential role in FA turnover at leading and trailing edge of cell are not yet fully understood. In this study, we investigate their spatial co-localisation with paxillin directly at leading and trailing edge of MDA-MB-231 breast cancer cell line. Materials and methods : Cell lines and cell culture experiments were done using MDA-MB-231human...
Topics: PtdIns(4, 5)P2, PtdIns(3, 4, 5)P3, Focal adhesions, Spatial co-localistion
Background: In cases of respiratory failure, Lung-Protective Ventilation Strategy (LPVS) which limits ventilator-induced lung injury is recommended. However, CO2 retention is a major impediment for LPVS and Extracorporeal membrane oxygenation (ECMO) supplies enough time to the lungs for rest and recovery. We aimed to find out the connection between ECMO usage and the reduction of mechanical ventilatory values in patients who required ECMO therapy after cardiac surgery due to pulmonary failure....
Topics: Extracorporeal membrane oxygenation, Lung-protective ventilation strategy, Cardiovascular surgery
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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We report a case of a 25-year-old male with a long history of watering from both the eyes. Complete ocular examination of the patient was carried out under slit lamp. Out of four, three punctums were found absent in our patient. Our case highlights a rare case of epiphora from both the eyes.
Topics: Punctum, Agenesis, Watering
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Topics: Pseudo prune belly syndrome, Abdominal wall laxity, Female
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : World Health Organization declared COVID-19 as a pandemic, and like any global health crisis at its beginning, need a commitment to take the necessary precautions due to its spread among people before and during the presence of vaccine or drug. This study aims to assess public opinion and practice of Libyan community in the context of the COVID-19 pandemic. Materials and methods : A cross-sectional online study was conducted among Libyans between Sep. 15th, and Oct. 29th, 2020...
Topics: Awareness, Coronavirus, COVID-19, Libyan people, Practice
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Problem-based learning (PBL) is a cornerstone of modern medical education. Principles of PBL are the construction of knowledge, prior knowledge activation, organization of knowledge, elaboration of knowledge, stepwise transfer across contexts and cooperation with other learners. It provides the ability to identify the knowledge, generate and analyze hypotheses that lead to the differential diagnosis of the case according to the complaint of the patient by using history taking, physical exam,...
Topics: Problem-Based Learning, Obstacles, Challenges, Medical Education
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : Over the past 10 years, much attention has been paid to the development of new antiviral drugs based on the suppression of the proteolytic activity of enzymes by trypsin inhibitors of plant and animal origin. Material and methods : We used a trypsin inhibitor from barley, trielin- (isolated by employees of the Agro-Industrial Institute of Selection and Genetics of the Ukrainian Academy of Sciences from the salivary glands of a dog); ovomukoid (isolated from duck eggs by employees...
Topics: Influenza virus, Tripsin-like proteinase, Inhibitor
This case report presents a lipofibromatous hamartoma of the median nerve in a 31-year-old man who presents local deformity and a sensory deficit in the nerve territory. The tumor was evaluated with magnetic resonance, computed tomography, and plain film radiography, studying the pathognomonic findings of this tumor. The patient did not want surgical treatment because of prior surgical sequelae. A prior surgical biopsy was reported as a peripheral nerve with normal axonal fascicles surrounded...
Topics: Lipofibromatous hamartoma, Median nerve, Carpal tunnel, Magnetic resonance, Macrodactyly
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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The relationship between the intra-abdominal pressure (IAP) and intracranial pressure (ICP) has been suspected for more than 100 years and was subsequently confirmed by numerous studies in both animals and humans which demonstrate the link and the positive correlation between IAP and ICP. There are mounting concerns that the pneumoperitoneum created during laparoscopic surgery to create space for instrument placement and to allow safe tissue dissection may result in an increase in the ICP...
Topics: Laparoscopy, Surgery, Ventriculoperitoneal shunts, Safety
Introduction : SARS-CoV-2 continues to raise health and socio-economical concerns globally. The recent discovery of the B.1.1.529 (Omicron) variant with its critical mutations has heightened the debate about the need for a better global vaccination rollout to prevent the emergence of new SARS-CoV-2 strains. Optimizing vaccine rollout in Africa is crucial for the management of the pandemic and preventing the rise of new strains. To better direct efforts and interventions it is important to know...
Topics: SARS-CoV-2, Africa, COVID-19, Vaccine, Immunology, New strains, International relations
Background : In cases of respiratory failure, Lung-Protective Ventilation Strategy (LPVS) which limits ventilator-induced lung injury is recommended. However, CO2 retention is a major impediment for LPVS and Extracorporeal membrane oxygenation (ECMO) supplies enough time to the lungs for rest and recovery. We aimed to find out the connection between ECMO usage and the reduction of mechanical ventilatory values in patients who required ECMO therapy after cardiac surgery due to pulmonary failure....
Topics: Extracorporeal membrane oxygenation, Lung-protective ventilation strategy, Cardiovascular surgery